In an interview with an American news channel Monday, Gilani said that Pakistan was re-evaluating its relationship with the United States.
He said Pakistan wanted to maintain its relationship with the United States as long as there was mutual respect for Pakistan's sovereignty.
Gilani highlighted incidents such as the killing of the Pakistani troops and a US raid into Pakistan to kill Osama bin Laden as violations of the country's sovereignty.
The prime minister also said Pakistan had not yet decided whether to boycott next month's Bonn conference on the future of Afghanistan.